A cortisone injection is a shot of steroid medicine used to calm pain and inflammation in a joint, tendon, or bursa (a small fluid-filled cushion near a joint).
It is most often given in the knee and shoulder, but it can also be used in the elbow, hip, ankle, wrist, and spine. For many people it offers real relief without surgery, and the effect can last for months.
What cortisone injections treat
Joints, tendons, and bursae let you move smoothly. When they become inflamed, the area gets painful, swollen, and stiff, and activity can hurt. A cortisone injection lowers that inflammation so the joint or tendon moves more comfortably.
It is used most for osteoarthritis, but it also helps joint pain from inflammatory arthritis (such as rheumatoid and psoriatic arthritis), gout, back pain, and irritation of a tendon or bursa.
Injections can be given in large joints (knee, hip, shoulder), medium joints (elbow, wrist, ankle), and small joints (fingers, toes). Because joint pain can also come from a fracture, a ligament injury, or an infection, your doctor first confirms what is actually causing it.
How cortisone works
Cortisone is a steroid, the same kind of substance your adrenal glands make naturally. Delivered right into the joint, tendon, or bursa, it quiets the local immune response and reduces inflammation. Less inflammation means less pain and swelling, which is what gives you the relief
When to consider a cortisone injection
A cortisone shot is usually considered when joint pain, swelling, or stiffness keeps going despite rest, ice, anti-inflammatory medicine, and easing off the activities that aggravate it.
It is a non-surgical option, often used to get inflammation under control so you can move and do your therapy. It is worth seeing a specialist when symptoms continue in spite of those first steps.
Benefits of cortisone injections
For the right problem, a cortisone injection has several upsides:
- Pain relief that can let you get back to activities the joint pain had made difficult.
- Better movement, since lowering inflammation improves how the joint works and its range of motion.
- A non-surgical option that can avoid or delay a more invasive procedure.
- Fairly fast results, with many people feeling better within a few days to a week.
- Relief that, while not permanent, often lasts several weeks to several months.
The cortisone injection procedure
The shot is done in the office as an outpatient procedure. First the physician checks that you are not on blood thinners and have no active infection. If you have diabetes, your blood sugar should be well controlled beforehand, because cortisone can raise it for a short time after the shot.
You are positioned so the joint is easy to reach, and the skin is cleaned with an antiseptic (alcohol swab). A numbing medicine is usually given along with the cortisone so the injection is more comfortable and you get some immediate relief.
The physician marks the spot, gives the injection, and covers it with a small dressing. Ultrasound can be used to guide the needle to exactly the right place.

Cortisone vial, alcohol swab, and the syringe.
Recovery and aftercare
Afterward, you can apply ice and take over-the-counter anti-inflammatory or pain medicine as needed for one to three days. Some mild pain or redness at the site is normal and usually settles within one to two days. Keep the dressing dry for at least a day and avoid hot tubs for a day, and watch for any signs of infection.
It is important to note that the local anesthetic will wear off in 24h and cortisone will typically take 48h to start working. Therefore, you may have some pain the next day. This is normal, because that is how the medications work. It is usually managed with over the counter pain medication, icing, and resting.
Risks and side effects
Cortisone injections are generally safe, but they do carry risks, which is why they are spaced out rather than repeated often. Getting them too frequently can damage cartilage or thin the bone and nearby tissue.
Other possible side effects include joint infection, nerve irritation, weakening of a nearby tendon, a brief increase in pain right after the shot, temporary facial flushing, and a short-term rise in blood sugar in people with diabetes
If you have a cortisone injection, and are planning to have a joint replacement surgery in the future, usually you must wait 3 months after the injection to get joint replacement. The injection increases your risk of infection during joint replacement, but returns to baseline after 3 months.
How long relief lasts
Most people feel relief within a few days. The pain reduction can last several months, and sometimes up to a year. It is not always permanent, so some people need a repeat injection if symptoms come back, spaced safely apart.
When to see a doctor
See a specialist if joint pain, swelling, or stiffness continues despite rest and medication. Seek emergency care if you develop severe redness, fever, pain you cannot control, or other signs of infection after the injection.
Insurance & Cost
Cortisone Injection at Complete Orthopedics is covered by Medicare and most major insurance carriers (Aetna, Anthem BCBS, Cigna, Empire BCBS, UnitedHealthcare), as well as most workers’ compensation and no-fault insurance plans. Your out-of-pocket cost depends on your specific plan, deductible, and the medical necessity criteria that apply to your case.
Call our billing team at (631) 981-2663 before scheduling to verify your coverage and discuss expected out-of-pocket costs. For the full list of carriers we accept and patient billing protections, see our Insurance Information page.
Do you have more questions?
How often can cortisone injections be administered?
Cortisone injections can be given every 3 months if necessary, but frequent injections may increase the risk of side effects.
Are cortisone injections suitable for all types of knee pain?
Cortisone injections are most effective for knee pain caused by inflammation, such as arthritis, bursitis, and tendinitis. They may not be as effective for other types of knee conditions, such as structural damage or severe degeneration.
Can cortisone injections be used alongside other treatments?
Yes, cortisone injections can be used in conjunction with other treatments such as physical therapy, medications, and lifestyle modifications to manage knee pain effectively.
Are there any alternatives to cortisone injections for knee pain relief?
Yes, alternatives include physical therapy, oral medications, hyaluronic acid injections, platelet-rich plasma (PRP) therapy, stem cell therapy, and surgical options for severe cases.
How soon after a cortisone injection can I resume normal activities?
You may be able to resume normal activities immediately after the injection, but it’s best to avoid strenuous activities for a day or two to allow the medication to take effect.
Can cortisone injections cause weight gain?
Cortisone injections can cause temporary fluid retention, which may lead to slight weight gain in some individuals. However, this effect is usually minor and resolves on its own.
Are cortisone injections safe for long-term use?
While cortisone injections are generally safe for occasional use, long-term use may increase the risk of side effects such as joint damage and osteoporosis.
Can cortisone injections worsen knee pain?
In rare cases, cortisone injections may initially worsen symptoms before providing relief. This is known as a “cortisone flare” and usually resolves on its own within a few days.
Are cortisone injections effective for all types of arthritis?
Cortisone injections can provide relief for arthritis-related knee pain, but their effectiveness may vary depending on the type and severity of arthritis.
Can cortisone injections be used to treat knee pain in children?
Cortisone injections may be considered for children with severe knee pain caused by conditions such as juvenile arthritis.
How do cortisone injections compare to other knee pain treatments in terms of effectiveness?
Cortisone injections are often effective for providing short-term pain relief and reducing inflammation.
Can cortisone injections be used to treat knee pain during pregnancy?
Cortisone injections are generally avoided during pregnancy.
Are cortisone injections covered by insurance?
Cortisone injections are typically covered by insurance when deemed medically necessary for the treatment of knee pain. However, coverage may vary depending on your insurance plan and specific circumstances.
Can cortisone injections be used to treat knee pain in athletes?
Cortisone injections may be considered for athletes with knee pain caused by inflammation or overuse injuries. However, it’s essential to weigh the potential benefits and risks, especially in high-performance athletes.
Can cortisone injections interfere with other medications I’m taking?
Cortisone injections may interact with certain medications, but this is rare.
Can cortisone injections be used to treat knee pain in older adults?
Cortisone injections can be used to treat knee pain in older adults, but they may be used cautiously due to the increased risk of side effects such as osteoporosis and joint damage.
Can cortisone injections be administered by a primary care physician, or do I need to see a specialist?
Cortisone injections can be administered by a primary care physician or a specialist such as an orthopedic surgeon or rheumatologist.



