Cervical Alignment and its Impact on Spinal Health

The main functions of the cervical spine are to maintain the position of the head in relation to the body and to control the level of horizontal gaze. The sagittal plane’s center of mass of the head is located directly above the occipital condyle, approximately one centimeter anterior and superior to the external auditory canal.

Any deviations from the typical alignment of the head’s mass will cause an increase in cantilever loads, leading to a rise in the amount of energy muscles need to expend. To describe the stability of the cervical spine, literature has divided its bone structure into three primary columns, one anterior and two posterior:

  • The vertebral bodies and discs make up the anterior column, while the two posterior columns are made up of the facet joints that articulate with each other.
  • The middle column is composed of the posterior half of the vertebral body, the posterior annulus fibrosis, and the posterior longitudinal ligament.
  • The ligamentous complex and the posterior arch make up the posterior column.

The head’s weight is supported by the condyle. This weight is then passed to a joint called C1-2 and divided into two parts – anterior column (including a disc between C2 and C3) and posterior column (including joints between C2 and C3).

Most of the weight is carried by the posterior column, which takes up about 64%, while the anterior column carries around 36%. The lumbar spine has been found to bear more weight in the front part (67% to 82%), and less weight in the back part (18% to 33%).

The cervical spine naturally has a curved shape called lordosis, which is created by the wedge-shaped cervical vertebrae and helps to balance out the curve in the thoracic spine called kyphosis. Kyphosis is a natural curve that allows the lungs to expand properly, but it can increase with age.

At the bottom of the lordotic curve, it meets the rigid kyphotic curve in the upper back, which is called the CTJ. Changes in the natural curvature, such as a loss of lordosis or the development of cervical kyphosis, are linked to pain and difficulty moving.

On the left, a normal cervical lordosis is shown with a small distance of 1.5 cm between the C-2 and C-7 plumb lines. On the right, cervical sagittal malalignment is shown with a large distance of more than 4 cm between the C-2 and C-7 plumb lines.

Cervical Lordosis Assessment Methods

There are three main ways to measure cervical lordosis:

  • Cobb angle method: It involves drawing two parallel lines – one along the bottom of the second vertebra (C-2) and one from the front of the first vertebra (C-1) to the back of the spinous process – as well as another line parallel to the bottom of the seventh vertebra (C-7). Then, perpendicular lines are drawn from each of the first two lines, and the angle where they meet is the angle of the cervical curvature.
  • Jackson physiological stress line method: Two lines are drawn parallel to the posterior surface of the C-7 and C-2 vertebrae. The angle between these two lines is then measured.
  • Harrison posterior tangent method: Lines are drawn parallel to the posterior surfaces of each cervical vertebra from C-2 to C-7, and the segmental angles are added together to obtain the overall curvature angle of the neck.

Literature has proposed that the Cobb angle measured from C1 to C7 can give a higher value for cervical lordosis, while the Cobb angle from C2 to C7 may give a lower value.

The Harrison method may provide a more accurate measurement, but it is not widely used due to its complexity. Nevertheless, the Cobb method is still commonly used in clinical settings due to its simplicity and reliability in measuring cervical lordosis.

Determining Cervical Lordosis using three different methods:

  • Cobb Angle Method
  • Jackson Physiological Stress Line Method
  • Harrison Posterior Tangent Method

SVA Measurement

There are various ways to measure the sagittal plane translation of the cervical spine, and one of them is through the use of cervical SVA (Sagittal Vertical Axis). The distance between the C-2 and C-7 plumb lines can be used to measure sagittal alignment globally.

This is done by measuring the C-2 SVA and C-7 SVA, which measure the distance between the posterior superior corner of the sacrum and the C-2 and C-7 plumb lines, respectively. Another way to measure cervical SVA is to use a regional approach, which involves measuring the distance between the posterosuperior aspect of C-7 and a plumb line dropped from the centroid of C-2 or the dens.

A new method to evaluate global sagittal alignment is the gravity line, which is measured from the center of gravity of the head and proposed as an alternative to the C-7 plumb line.

Using a plumb line from the center of gravity of the head, instead of C-2, can also be applied to assess regional cervical SVA. The center of gravity of the head can be estimated on lateral X-rays by using the front part of the external auditory canal as a starting point for the plumb line.

The C-2 plumb line holds significant clinical importance as it has a direct association with Health-Related Quality of Life (HRQOL). An increase in C-2 SVA has been linked to lower HRQOL, making it a crucial factor in assessing the patient’s overall condition.

CBVA Measurement

The CBVA is a measure of the direction of a person’s gaze. It is particularly valuable when dealing with severe, inflexible cervical kyphotic deformities since the inability to maintain a horizontal gaze can significantly affect one’s quality of life and daily activities.

The CBVA is calculated by measuring the angle between a line drawn from the patient’s chin to brow and a vertical line. This angle is determined from clinical photographs of the patient, taken while standing with their hips and knees extended and their neck in a neutral or fixed position.

Relationship Between Thoracic and Neck Tilts with Cervical Alignment

The alignment of the cervical spine has been observed to have a correlation with several factors, including the thoracic inlet angle, neck tilt, cervical tilt, and cranial tilt.

Thoracic inlet angle is determined by measuring the angle between two lines. One line starts from the center of the T-1 endplate and is perpendicular to the T-1 endplate. The other line connects the center of the T-1 endplate to the upper end of the sternum.

Neck tilt is an angle measured between two lines that start from the upper end of the sternum. One line is a vertical line, while the other line connects to the center of the T-1 endplate.

Cervical tilt is determined by measuring the angle between two lines that originate from the center of the T-1 upper endplate. One line is perpendicular to the T-1 endplate, while the other line passes through the tip of the dens.

Cranial tilt is defined as an angle between two lines that originate from the center of the T-1 upper endplate. One line passes through the dens, which is the same as the second line in cervical tilt, while the other line is a vertical line.

There is a correlation between the thoracic inlet angle and the T-1 slope, which is the angle between a horizontal plane and a line that is parallel to the superior endplate of T-1, as well as the neck tilt

Normal Cervical Alignment

Various normal alignment ranges have been described for the cervical spine due to its high mobility. In individuals without any spinal problems, it has been observed that a significant proportion (around 75%-80%) of the normal curvature of the cervical spine when standing is concentrated around the C1-2 level, while there is relatively lesser curvature present in the lower cervical levels. The majority of the lumbar curvature is located at the lower end, with the L5-S1 level having the highest degree of curvature angle.

The curvature of the cervical spine may be influenced by the structure of the cervicothoracic junction (CTJ), which usually includes the C-7 and T-1 vertebrae, the discs between C1 and C7, and the ligaments connecting them. When planning for surgical procedures, it may be necessary to consider the structure of the CTJ as far up as T-2 or T-3.

The CTJ, which encompasses the junction between the cervical and thoracic spine, includes a rigid osseous ring called the thoracic inlet. This bony structure is made up of the first ribs, T-1 vertebra, and upper sternum.

The CTJ refers to the area where the cervical spine, which supports the head, transitions into the thoracic spine, which is relatively rigid due to the presence of the rib cage. In this area, the curvature of the cervical spine changes to the curvature of the thoracic spine, leading to stress on the CTJ, both in static and dynamic states. This stress can have implications for spinal alignment and overall health.

The shape and orientation of the thoracic inlet can affect the position of the cranium and cervical spine in the sagittal plane, which is important for maintaining an upright posture and level gaze. This relationship is similar to the relationship between pelvic incidence and lumbar lordosis.

Different parts of the spine, such as the cervical, thoracic, lumbar, and pelvis regions, are not isolated from each other and there are several important connections or relationships that exist among them.

Pelvic incidence is related to the curvature of the lumbar spine, which is then related to the curvature of the thoracic spine, and finally related to the curvature of the cervical spine. There are correlations between all these spinal regions, indicating that they are not independent of each other.

Therefore, a rise in pelvic incidence is related to a rise in lumbar lordosis, which in turn is associated with an increase in thoracic kyphosis, which further associates with an increase in cervical lordosis.

Cervical lordosis can be considered as an adaptive spinal segment to global alignment, which correlates with lumbar lordosis and thoracic kyphosis. When lumbar lordosis and thoracic kyphosis are adapted to the patient’s pelvic incidence, the amount of cervical lordosis will be proportional to the other curves.

However, an increase in cervical lordosis is a compensatory mechanism when the patient has an anterior malalignment of the spine, whereas if a primary cervical deformity exists, changes in the lumbar spine and pelvis will attempt to compensate.

Cervical Deformity

Cervical spine deformities can occur in both sagittal and coronal planes, but sagittal plane deformities are more prevalent and surgical correction of these deformities is crucial for achieving favorable clinical outcomes.The cervical spine deformity can be classified as either primary or secondary:

  • Primary: Often congenital
  • Secondary: are caused by iatrogenic factors or ankylosing spondylitis, a condition characterized by the fusion of the joints and ligaments in the spine.

If primary spinal deformities in one area are not treated, they can cause secondary deformities in other regions because the entire spine operates as a single global unit, and the individual regions can strongly impact each other.

Prevalent Deformities

Cervical kyphosis is the most commonly occurring deformity in the cervical spine, and it is often caused by medical treatment, such as postlaminectomy kyphosis. When the spinal cord passes over the deformity, it may get compressed, resulting in various disabling symptoms.

Such as myelopathy, difficulty in looking straight ahead, and difficulty in swallowing. The main objectives of the surgical procedure are to correct and stabilize the deformity, decompress the neural components, and restore the sagittal alignment.

One should acknowledge that while cervical sagittal alignment (cervical SVA) is closely linked to the cervical sagittal Cobb angle (C2-7 Cobb angle), which measures the curvature of the spine, the former also considers the alignment of underlying segments, such as the thoracolumbar spine and pelvis.

Cervical Deformity Surgery

The primary goals of surgery for cervical deformities are to restore the normative alignment of the cervical spine, decompress neural components, and maintain or restore the ability to look straight ahead. In preoperative planning and postoperative evaluation, radiographic parameters such as Cobb angles for kyphosis, C1-2 lordosis, and C2-7 lordosis are commonly used to measure regional changes.

Despite the increasing evidence connecting radiographic parameters and clinical outcomes, most studies are limited by their retrospective design. Furthermore, these studies tend to overlook the potential benefits of spinal cord decompression in the surgical procedures.

Analyzing cervical regional alignment in relation to overall spinal pelvic alignment is crucial to gain a comprehensive understanding of the impact of cervical deformity on patient outcomes.

Cervical Deformity and ASD

The adjacent-segment disease of the cervical spine is defined as the occurrence of new radiculopathy or myelopathy in a motion segment adjacent to a previous arthrodesis of the spine, whether it is superior or inferior.

The correlation between cervical deformity and adjacent segment disease (ASD) has not been studied as extensively as other topics but requires considerable attention.

The cervical spine’s natural lordotic curvature allows it to distribute the load of the head between the posterior and anterior columns. The posterior columns, including the articular processes and facet joints, withstand about 64% of the load, while the anterior column withstands approximately 36%.

Cervical Deformity and Myelopathy

Spinal cord dysfunction due to cervical spondylotic myelopathy is frequently observed in patients aged over 55 years. The most frequent complaints related to cervical spondylotic myelopathy are motor and sensory dysfunction. Often, legs experience these symptoms.

Myelopathy has also been linked to the development of progressive cervical kyphosis, causing the spinal cord to drape over the vertebral bodies and anterior pathology, increasing longitudinal cord tension. The dentate ligaments and cervical nerve roots contribute to this phenomenon by tethering the spinal cord.

When treating cervical myelopathy, it is important to consider the sagittal alignment of the cervical spine, which can impact the approach and the origin and progression of the myelopathy. Merely performing decompression, including ventral decompression, without addressing the cord tension caused by kyphosis, may not lead to the best possible results.

Correcting cervical lordotic alignment in the subaxial spine above C-7 may not always be feasible using only a posterior approach. In some cases, it may be necessary to use an anterior approach and reconstruct the area with lordotic interbody spacers to restore the natural lordotic curve of the cervical spine.

Surgically managing cervical disease is a significant challenge due to the complexity of the cervical spine. To effectively handle complex cervical pathology, it is essential to have knowledge of cervical biomechanics and normative data for cervical alignment.

If you are interested in knowing more about cervical spine alignment, sagittal deformity, and clinical implications you have come to the right place!

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Dr. Nakul Karkare is awesome! And patriotic! Thank you, Dr. Karkare for displaying the American Flag in your waiting room, honoring and mourning our military personnel, this Memorial Day, who died while serving in the United States Armed Forces.
00:52 30 May 23
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00:24 30 May 23
I had such a wonderful experience with Complete Orthopedics in Stony Brook. Not only did Dr. Kuo fix my broken wrist with such kindness and care, but the office staff, including Billing, Reception and the X-Ray Technician, was always so helpful, going out of their way to ensure that each patient felt welcome, answering any questions with a smile, and ensuring any issues with insurance/billing were handled with the utmost professionalism. I highly recommend their practice!
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I'm very happy St. Catherine's sent me to this office for treatment after I broke my collar bone! Unfortunately the break was too severe to repair on its own and I had to have it rebuilt a week after the injury. Dr. Vaksha did a great job fixing it. I'm three months out, and I have full use of the arm and shoulder. The whole office staff is very professional, accommodating, and welcoming. I hope to not need orthopedic services again, but Dr. Vaksha will be my number one choice if I or anyone in family suffers such am injury.
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21:28 23 May 22
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19:54 16 May 22
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23:17 12 May 22
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16:06 01 Apr 22
Brand new office, same great doctors! Rooms are clean, plenty of parking, physical therapy attached, Dr. Karkare and his staff are awesome. Thank you!
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01:24 23 Feb 22
After suffering from a severe ankle injury Dr. V was able to help me heal and return back to work completely to a job where I stand for 12 hours a day. The office is very clean and I appreciated the reminders of my appointments via phone call and through text. The patient portal made it easy for me to access all my documents including work notes. The office staff is wonderful and Rebecca was able to schedule me with a busy schedule and awesome at answering all of my questions including referring me to a great physical therapy office. I highly recommend this office to anyone who’s looking for knowledgeable and kind orthopedic office.
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18:14 07 Jan 21
They are an excellent practice. The front and back office people are amazing and so helpful. Rebecca is such a kind and understanding person. I had an issue with paperwork and she cleared it right up. Dr. Karkare is very knowledgeable, helpful, and caring.
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17:26 17 Nov 20
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I was rear ended in an auto accident , Dr Vashka was recommended by a friend of mine .I was experiencing Back , neck , and shoulder pain . After a thorough examination and given exercises to do at home , I am feeling much better , and I ended up avoiding surgery . The staff at Complete Ortho is extremely attentive and show great care when making an appointment and are very friendly and i never waited more than 5 minutes for my appointment . So I would strongly recommend Complete Orthopedics for any aches and pains that one might be experiencing.....
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04:44 17 Nov 20
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Jack Harris
14:36 06 Nov 20
In the year of 2018 I was referred to Dr. Karkare because I was experiencing severe knee joint pain. After exhausting physical therapy and trying to labor through the pain, I had to make a quality of life decision. Total knee replacement was the only viable option. Dr. Karkare made my decision easy as he walked me through the whole process from surgery to recovery.On 12/13/19 ( Friday the 13th) I enter Lenox Hill Hospital in great hands. From the time I entered Dr. Karkare’s office for the first time until now, his staff has been amazing. Andrea the medical coordinator walked me through all the paper work and necessary preparations for the surgery. Courtesy and kind would be an understatement. Dr. Karkare went over and beyond from the wellness checks and phone calls all to assure me that I was important to him. This was the right decision no pain and no limp. Complete Orthopedics should be your choice!
Kenneth Randolph
22:18 25 Sep 20
Dr. Vadshka has a great bedside manner. He really takes his time and explains treatment options.
T Lee
12:33 09 Sep 20
I suffered with pain in both knees for years. My orthopedic doctor kept recommending knee replacement . I fought it for years, as I was just afraid. When I had no choice and could barely walk , it was recommended I see Dr. Karkare. We set up a consultation and my wife and I left his office feeling totally confident and comfortable with moving ahead with the surgery. He explained everything to us, and the office staff set everything up for us and made the process easy. So about one month after our initial meeting I had the first knee done. I was up walking mere hours after the surgery, and on the workout machines the next morning. I went home two days after the surgery, and yes walked my daughter down the aisle at her wedding only one week after the surgery without even a cane! Three months later I had the other knee done and went home the very next day. Dr. Karkare put my fears to rest . I would highly recommend him. His expertise gave me my life back. Thank you Dr. Karkare.SincerelyVito Congro
Ethel Congo
23:58 12 Aug 20
Dr Rhodin really cares for his patients. When I see him he makes sure to review my progress in detail.
Micki Cahill
15:03 08 Feb 20
My mom had a total hip replacement by dr karkare. He is the BEST orthopedic doctor.Her incision is almost invisable.She is going back for her other hip next week. The office staff is the best, love Andrea.You wont find a better doctor.
Ryan Brigandi
21:06 13 Jul 18
There is no better Orthopedic doctor you will find. Broke my ankle three places on a Saturday. Called Dr. Karkare. He had is team ready at the hospital and operated on me within 6 hours after my injury. Now After 3 months of great care by him and his staff, I am walking to normalcy.
Spacecom Tel
04:13 23 Mar 18

I am Vedant Vaksha, Fellowship trained Spine, Sports and Arthroscopic Surgeon at Complete Orthopedics. I take care of patients with ailments of the neck, back, shoulder, knee, elbow and ankle. I personally approve this content and have written most of it myself.

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