Surgical Considerations for Ossification of

Posterior Longitudinal Ligament (OPLL)

At Complete Orthopedics, our surgeons specialize in the treatment of complex spine conditions such as ossification of the posterior longitudinal ligament, or OPLL. We carefully plan every step of surgery to maximize benefits, minimize risks, and ensure safe recovery. Each patient receives a customized approach based on their anatomy, imaging results, and overall health.

Our offices are located throughout New York City and Long Island, with privileges at six leading hospitals that provide the latest surgical technology and advanced spinal monitoring systems.

How Common It Is and Who Gets It? (Epidemiology)

OPLL is most often seen in middle-aged and older adults, particularly in individuals of Asian descent, though it occurs worldwide. The condition tends to develop gradually and may not cause symptoms until the ossified (hardened) ligament begins pressing on the spinal cord. Men are affected slightly more often than women.

Why It Happens – Causes (Etiology and Pathophysiology)

OPLL occurs when a ligament that runs along the back of the spine’s vertebral bodies—called the posterior longitudinal ligament—gradually turns into bone. This thickened, hardened tissue can narrow the spinal canal and compress the spinal cord or nerves.

The exact cause is unknown, but aging, genetics, diabetes, and minor repetitive injuries to the spine may contribute. In some people, the spinal canal is naturally narrow (a condition known as congenital stenosis), making them more likely to develop symptoms if ossification occurs.

How the Body Part Normally Works? (Relevant Anatomy)

The posterior longitudinal ligament runs along the back surface of the vertebral bodies inside the spinal canal. Its job is to stabilize the spine and limit excessive movement. When the ligament thickens and hardens, it takes up space in the canal, squeezing the spinal cord. This pressure can interrupt signals between the brain and body, leading to numbness, weakness, or coordination problems.

What You Might Feel – Symptoms (Clinical Presentation)

Symptoms depend on how much the spinal cord is compressed. Common signs include:

  • Neck stiffness or aching

  • Numbness or tingling in the hands, arms, or legs

  • Weakness or clumsiness of the hands

  • Unsteady gait or loss of balance

  • Electrical shock-like sensations when bending the neck

  • In more severe cases, difficulty controlling bladder or bowel function

How Doctors Find the Problem? (Diagnosis and Imaging)

Diagnosis begins with a physical exam to assess strength, sensation, and coordination.

Imaging is crucial to confirm the diagnosis and plan treatment:

  • MRI scans show pressure on the spinal cord and detect inflammation or swelling.

  • CT scans clearly show the hardened ligament and help classify the type of OPLL.

OPLL is typically divided into four types: segmental, continuous, mixed, and localized (other). Understanding which type a patient has helps surgeons choose the safest approach.

Classification

OPLL is classified based on the shape and distribution of the ossification:

  • Segmental: Small, separate areas of bone formation behind individual vertebrae.

  • Continuous: A long stretch of bone extending across multiple vertebrae.

  • Mixed: Features of both continuous and segmental patterns.

  • Localized/Other: Limited to a small area or atypical pattern.

Other Problems That Can Feel Similar (Differential Diagnosis)

Conditions that can mimic OPLL include:

  • Cervical spondylotic myelopathy (spinal cord compression from arthritis)

  • Herniated cervical discs

  • Spinal tumors or infections

  • Inflammatory disorders such as ankylosing spondylitis

MRI and CT imaging help rule out these other causes.

Treatment Options

Non-Surgical Care

If symptoms are mild, OPLL may be managed conservatively with:

  • Physical therapy and posture correction

  • Medications to relieve pain and stiffness

  • Regular monitoring with MRI to detect progression

However, once neurological symptoms such as weakness, numbness, or walking imbalance appear, surgery is usually required to prevent worsening.

Surgical Care

Surgery aims to relieve pressure on the spinal cord and stabilize the spine. The approach depends on spinal alignment, location of the ossified ligament, and number of levels involved.

Posterior (Back) Surgery
If the spine retains a normal forward curve (lordosis), decompression through the back—such as laminoplasty or laminectomy and fusion—is preferred. These methods relieve pressure without the risks associated with operating from the front of the neck.

Anterior (Front) Surgery
If the spine has lost its normal curve or is bent forward (kyphosis), surgery from the front may be needed. Procedures such as corpectomy (removal of part of the vertebral body) allow direct removal of the ossified ligament.

Each approach has unique advantages and risks, and the final decision is made based on detailed imaging and patient factors.

Recovery and What to Expect After Treatment

After OPLL surgery, patients typically stay in the hospital for several days. Early movement and physical therapy are encouraged to maintain flexibility and prevent stiffness.

Rehabilitation focuses on:

  • Restoring strength and coordination

  • Practicing proper neck alignment and movement

  • Preventing recurrence through gentle exercise and posture training

Patients are advised to avoid heavy lifting or activities that strain the neck during recovery.

Possible Risks or Side Effects (Complications)

As with any spine surgery, complications can occur but are minimized through careful planning. Potential risks include:

  • Infection or bleeding

  • Nerve injury or spinal fluid leak

  • Difficulty swallowing (after anterior surgery)

  • Wound healing issues (especially after prior radiation)

  • Hardware failure or need for revision surgery

Elderly patients and those with extensive ossification may have slightly higher complication risks.

Long-Term Outlook (Prognosis)

Surgery for OPLL generally leads to significant improvement in pain, strength, and balance. The degree of recovery depends on how much spinal cord damage occurred before surgery. Most patients report improved quality of life and reduced risk of sudden paralysis after successful decompression and stabilization.

Out-of-Pocket Cost

Medicare

CPT Code 63050 – Posterior Cervical Laminoplasty: $362.34

For patients under Medicare, the program covers approximately 80% of the approved amount for this type of cervical spine surgery once the annual deductible has been met. The remaining 20% is typically the patient’s responsibility. However, supplemental insurance plans such as Medigap, AARP, or Blue Cross Blue Shield usually cover this 20% coinsurance, meaning patients often have no additional expenses for Medicare-approved procedures. These plans are structured to work in conjunction with Medicare, ensuring comprehensive coverage for necessary surgical care.

Secondary insurance—such as Employer-Based Plans, TRICARE, or Veterans Health Administration (VHA)—acts as a secondary payer after Medicare. Once your deductible is satisfied, these plans may cover any remaining costs, including co-insurance or uncovered charges. Most secondary insurance plans carry a modest deductible ranging from $100 to $300, depending on the specific policy and whether the procedure is performed at an in-network facility.

Workers’ Compensation
If your OPLL (Ossification of the Posterior Longitudinal Ligament) with cervical lordosis is related to a work injury, Workers’ Compensation will pay for all treatment-related expenses. This includes the laminoplasty, hospital stay, and rehabilitation, with no out-of-pocket cost to the patient.

No-Fault Insurance
If your spinal condition was aggravated or caused by a motor vehicle accident, No-Fault Insurance will fully cover all medical and surgical costs associated with your OPLL treatment, including posterior laminoplasty. The only potential charge would be a small deductible, depending on your individual insurance policy terms.

Example
Robert, a 61-year-old patient with cervical OPLL and progressive lordosis, underwent a posterior laminoplasty (CPT 63050). His estimated Medicare out-of-pocket cost was $362.34. Since Robert carried supplemental insurance through Blue Cross Blue Shield, the remaining 20% portion not paid by Medicare was fully covered, leaving him with no out-of-pocket expense for the surgery.

Frequently Asked Questions (FAQ)

Q. Is surgery always necessary for OPLL?
A. No. If symptoms are mild and stable, your doctor may recommend monitoring and physical therapy. Surgery is advised if nerve compression worsens.

Q. Which surgery is safer—anterior or posterior?
A. Each approach has its place. Posterior surgery avoids major front-of-neck structures, while anterior surgery allows direct removal of the ossified ligament in certain cases. Your surgeon will determine which is best for your spine alignment and anatomy.

Q. How long does recovery take?
A. Most patients return to light activities within a few weeks and continue improving for several months with therapy.

Q. Can OPLL return after surgery?
A. It’s uncommon, but ossification may slowly progress over time. Regular follow-up imaging helps monitor any changes.

Summary and Takeaway

Ossification of the posterior longitudinal ligament (OPLL) is a condition where a spinal ligament hardens and presses on the spinal cord. When symptoms progress, surgery is the most effective way to relieve pressure and protect nerve function. With careful surgical planning and rehabilitation, most patients experience meaningful pain relief, improved mobility, and long-term stability.

Clinical Insight & Recent Findings

A recent study developed a predictive model to identify patients at higher risk of postoperative ossification progression following cervical surgery for ossification of the posterior longitudinal ligament (OPLL). The study analyzed 271 patients and found that younger age, greater initial ossification thickness, involvement of more than three spinal levels, and continuous or mixed OPLL types were independent risk factors for disease progression after posterior surgery.

Using these factors, researchers created a nomogram—a clinical tool that allows surgeons to estimate the likelihood of postoperative ossification growth and tailor follow-up or rehabilitation accordingly. The model demonstrated strong accuracy, with a C-index above 0.9 in both training and validation sets, and its decision curve analysis confirmed significant clinical value.

These findings emphasize the importance of careful preoperative planning, patient selection, and long-term monitoring to prevent progression and improve surgical outcomes in OPLL. (Study of postoperative ossification progression risk modeling in OPLL – See PubMed.)

Who Performs This Treatment? (Specialists and Team Involved)

Treatment is performed by orthopedic spine surgeons or neurosurgeons experienced in complex cervical procedures. The team also includes anesthesiologists, neurophysiologists, and rehabilitation specialists to ensure safe surgery and full recovery.

When to See a Specialist?

You should see a spine specialist if you experience:

  • Progressive neck stiffness or pain

  • Numbness or weakness in the arms or legs

  • Trouble with coordination or balance

  • Difficulty controlling bladder or bowel function

When to Go to the Emergency Room?

Go to the ER if you experience:

  • Sudden paralysis or severe weakness

  • Loss of bladder or bowel control

  • New or worsening numbness in the hands or feet

These are signs of spinal cord compression that require urgent care.

What Recovery Really Looks Like?

After surgery, most patients notice gradual improvement in strength and coordination. Neck soreness is normal at first but lessens with time. Physical therapy helps restore mobility and ensures proper spinal alignment during healing.

What Happens If You Ignore It?

Untreated OPLL can lead to progressive spinal cord damage, increasing the risk of paralysis even from minor injury. Early diagnosis and timely treatment are essential for preventing irreversible nerve damage.

How to Prevent It?

While OPLL cannot always be prevented, maintaining a healthy lifestyle and protecting spinal health can help:

  • Maintain good posture and neck alignment

  • Avoid repetitive strain or high-impact sports

  • Keep a healthy weight and manage chronic conditions like diabetes

  • Schedule regular checkups if you have a family history of OPLL

Nutrition and Bone or Joint Health

A balanced diet with calcium, vitamin D, and protein supports bone health and recovery after surgery. Avoid smoking and excessive alcohol, as they can weaken bone and delay healing.

Activity and Lifestyle Modifications

After recovery, continue gentle exercises such as walking or swimming. Avoid sudden neck movements and heavy lifting. Good ergonomics at work and home—such as proper desk height and supportive seating—help protect your spine long-term.

Do you have more questions? 

What causes OPLL?

The exact cause is unknown, but it is believed to be due to a combination of genetic, hormonal, and environmental factors. There are associations with conditions like diabetes and obesity, and it is more common in East Asian populations​

How is OPLL diagnosed?

Diagnosis typically involves a combination of patient history, physical examination, and imaging studies like X-rays, MRI, and CT scans to identify the ossification and assess the extent of spinal cord compression​

What are the symptoms of OPLL?

Symptoms include neck pain and stiffness, radiating pain to the shoulders and arms, numbness or tingling in the hands, weakness in the arms and legs, difficulty with coordination and balance, and in severe cases, paralysis or bladder and bowel dysfunction

What non-surgical treatments are available for OPLL?

Non-surgical treatments include pain relievers, anti-inflammatory drugs, muscle relaxants, physical therapy, and lifestyle modifications such as weight management and avoiding activities that exacerbate symptoms​

What surgical options are available for treating OPLL?

Surgical options include anterior approaches like ACDF and corpectomy, posterior approaches like laminoplasty and laminectomy, and sometimes combined approaches for more extensive cases

When is surgery recommended for OPLL?

Surgery is recommended when conservative treatments fail to relieve symptoms or if there is significant spinal cord compression that poses a risk of severe neurological damage

What is the recovery process like after OPLL surgery?

Recovery involves rest, medication, and physical therapy. Patients are typically advised to follow a tailored physical therapy program, avoid strain on the neck and spine, and monitor for complications​

How successful is OPLL surgery?

Surgical outcomes are generally favorable, with many patients experiencing significant relief from symptoms and improved quality of life. However, some may continue to have residual symptoms or complications​

What are the risks associated with OPLL surgery?

Risks include infection, bleeding, spinal fluid leakage, nerve damage, and worsening of neurological symptoms due to spinal cord manipulation​

Can OPLL recur after surgery?

While surgery can relieve symptoms and stabilize the spine, there is a risk of recurrence. Ongoing follow-up and possibly further treatment may be necessary​

What role does genetics play in OPLL?

Genetics is believed to play a significant role in OPLL, with certain genetic markers associated with an increased risk. This is particularly evident in populations with a higher prevalence of the condition

Are there any lifestyle changes that can help manage OPLL?

Yes, weight management, proper posture, regular exercise, and avoiding activities that strain the neck and spine can help manage OPLL symptoms​

How does OPLL progress over time?

OPLL can progress slowly, with gradual worsening of symptoms as the ossification increases and further compresses the spinal cord and nerves. Early intervention can help manage the progression

Can physical therapy help with OPLL?

Yes, physical therapy can help strengthen the neck muscles, improve flexibility, and reduce pain. A tailored physical therapy program is an important part of both conservative treatment and postoperative recovery​

Is there a cure for OPLL?

There is no cure for OPLL, but treatments can effectively manage symptoms and prevent further progression. Research into the genetic and molecular mechanisms of OPLL may lead to new therapeutic approaches in the future

What is the difference between laminoplasty and laminectomy?

Laminoplasty involves reshaping or repositioning the lamina to relieve pressure on the spinal cord while maintaining stability. Laminectomy involves removing the lamina to create more space for the spinal cord, often combined with spinal fusion for stability

How long does it take to recover from OPLL surgery?

Recovery time varies depending on the type of surgery and the patient’s overall health, but it typically takes several weeks to months. Full recovery and return to normal activities can take up to a year​

What are the potential complications of not treating OPLL?

Untreated OPLL can lead to severe spinal cord compression, resulting in chronic pain, significant neurological deficits, and in extreme cases, paralysis and loss of bladder and bowel control​

Can children develop OPLL?

OPLL is rare in children and is more commonly seen in middle-aged and older adults. However, it can occur in younger individuals, particularly those with a genetic predisposition

How does OPLL differ from other spinal conditions like spondylosis or disc herniation?

OPLL involves the ossification of a specific spinal ligament, whereas spondylosis refers to general degenerative changes in the spine, and disc herniation involves the displacement of the intervertebral disc material. Each condition has distinct causes, symptoms, and treatment approaches​

Are there any new treatments or research developments for OPLL?

Research is ongoing to better understand the genetic and molecular mechanisms of OPLL, which may lead to new treatments. Advances in imaging and surgical techniques are also improving the diagnosis and management of the condition

What should I do if I suspect I have OPLL?

If you have symptoms suggestive of OPLL, such as neck pain, numbness, or weakness, you should seek medical evaluation. An orthopedic surgeon or spine specialist can perform the necessary diagnostic tests and recommend appropriate treatment

Can OPLL affect other parts of the spine besides the cervical region?

Yes, while OPLL is most commonly found in the cervical spine, it can also occur in the thoracic and lumbar regions, though less frequently​

How does the surgical approach for OPLL get decided?

The choice of surgical approach depends on the extent and location of ossification, the patient’s overall health, and the surgeon’s experience. Detailed imaging studies and thorough patient evaluation guide the decision-making process

Dr Vedant Vaksha
Dr. Vedant Vaksha

I am Vedant Vaksha, Fellowship trained Spine, Sports and Arthroscopic Surgeon at Complete Orthopedics. I take care of patients with ailments of the neck, back, shoulder, knee, elbow and ankle. I personally approve this content and have written most of it myself.

Please take a look at my profile page and don't hesitate to come in and talk.

 

D10x