Total Disc Replacement
Total disc replacement (TDR) is a surgical procedure designed to replace a damaged intervertebral disc with an artificial prosthetic disc, restoring the spine’s mobility and alleviating pain. It is performed primarily in the cervical and lumbar regions of the spine, where degenerative disc disease or herniated discs cause significant pain and disability.
How Common It Is and Who Gets It? (Epidemiology)
Disc degeneration and herniation are common causes of back and neck pain. A growing number of patients are undergoing total disc replacement, particularly those with persistent symptoms of radiculopathy from a herniated or damaged disc that has not responded to conservative treatments. Most candidates for TDR are between the ages of 30 and 60, with a higher prevalence in individuals involved in manual labor or those with sedentary lifestyles contributing to spinal wear and tear.
Why It Happens – Causes (Etiology and Pathophysiology)
The intervertebral disc is a gel-like structure that cushions the vertebrae and allows for spinal mobility. Over time, wear and tear, trauma, or degenerative changes, such as decreased hydration in the disc’s nucleus pulposus, can lead to disc herniation or bulging. These conditions compress nearby nerve roots or the spinal cord, causing pain, weakness, numbness, and in severe cases, loss of mobility. Obesity, smoking, poor posture, and repetitive strain are contributing factors to disc degeneration and herniation.

Axial section of the cervical spine showing disk herniation on MRI.
How the Body Part Normally Works? (Relevant Anatomy)
The intervertebral discs are located between the vertebrae and serve as shock absorbers, allowing the spine to flex, extend, and rotate. Each disc consists of two parts: the nucleus pulposus, a gel-like center, and the annulus fibrosus, the tough outer ring. The discs also maintain the space between vertebrae, enabling the nerve roots to exit the spinal cord without compression.
What You Might Feel – Symptoms (Clinical Presentation)
Symptoms of a damaged or herniated disc can include sharp, radiating pain in the neck or lower back, which may extend down the arms or legs. Patients often experience tingling, numbness, or weakness in the affected limbs. In more severe cases, patients may suffer from reduced mobility, and in extreme cases, motor deficits or bowel and bladder dysfunction may occur.
How Doctors Find the Problem? (Diagnosis and Imaging)
Diagnosis is confirmed through clinical examination and imaging studies. An MRI is the gold standard for identifying disc herniation, disc degeneration, and nerve root compression. In cases of cervical or lumbar pain, MRI scans will reveal the location and extent of the herniation, the condition of the discs, and any impingement on the nerves or spinal cord.

Total cervical disc replacement
The image above shows a total cervical disc replacement along with various parts of the cervical vertebra. The components of the total cervical disc replacement include metal parts attached on the adjoining vertebrae to create the space for the prosthetic disc. The prosthetic disc is usually made of a PEEK (poly-ether-ether-ketone) polymer.
Classification
Total disc replacement is typically indicated for patients with single-level or multi-level disc degeneration or herniation. Candidates must have no significant facet joint arthritis or spinal instability, as these conditions could complicate the procedure. TDR is classified based on the location of the disc herniation—cervical or lumbar—and the type of prosthetic disc used.
Other Problems That Can Feel Similar (Differential Diagnosis)
Conditions that can mimic the symptoms of disc herniation include facet joint arthritis, spinal stenosis, piriformis syndrome, and muscle strains. Infections or tumors in the spine can also present with similar symptoms, necessitating a thorough work-up to rule out other conditions.
Treatment Options
Non-Surgical Care
Conservative treatment for disc herniation includes physical therapy, anti-inflammatory medications (NSAIDs), heat or cold therapy, and spinal injections such as epidural steroid injections. If conservative methods fail, surgical intervention may be considered, with TDR as an option for suitable candidates.
Surgical Care
Total disc replacement involves the removal of the damaged disc and insertion of an artificial disc to maintain motion at the affected segment. Other surgical options include spinal fusion, but fusion does not preserve motion in the affected segment, which TDR aims to do.
Recovery and What to Expect After Treatment
Postoperative recovery for total disc replacement generally takes about 6 weeks, with patients gradually returning to normal activities. During the rehabilitation period, patients focus on strengthening the muscles around the spine to support the new disc. Most patients report a significant reduction in pain and improvement in function.
Possible Risks or Side Effects (Complications)
As with any surgery, total disc replacement carries potential risks, including infection, bleeding, nerve injury, implant failure, and the development of adjacent segment disease (additional degeneration in nearby discs). Long-term complications could include disc displacement or wear and tear of the prosthetic.
Long-Term Outlook (Prognosis)
The prognosis for patients undergoing TDR is generally positive, with most patients experiencing significant pain relief and restored mobility. However, the long-term success of the procedure depends on factors such as the quality of the implant, patient adherence to rehabilitation, and the absence of other spinal diseases.

Instruments used during a total cervical disc replacement
The instruments shown in the image above are used during the surgery to remove the diseased disc, create raw bone surface for implanting the metal endplates and subsequent insertion of the prosthetic disc.

Trial cervical disc replacement bearings
The trial cervical discs are used to find the correct size of the final cervical prosthetic disc for maximum stability and motion.
Do you have more questions?
What materials are used in artificial discs?
Artificial discs are typically made from metal alloys such as titanium or cobalt-chromium and a medical-grade plastic called polyethylene. These materials are chosen for their strength, durability, and compatibility with the human body, ensuring they can withstand the stresses of daily activities
What are the chances of needing additional surgery after CTDR?
The likelihood of needing additional surgery is lower with CTDR compared to spinal fusion, especially concerning adjacent segment disease. However, some patients might still require further surgical interventions if complications arise or symptoms persist
Are there any activities I should avoid after CTDR?
Initially, you should avoid heavy lifting, repetitive neck movements, and high-impact activities. Your surgeon will provide specific guidelines based on your recovery progress. Gradually, you will be able to resume most activities as your neck heals
How does CTDR compare to spinal fusion in terms of pain relief?
Studies have shown that CTDR provides comparable, if not superior, pain relief compared to spinal fusion. Additionally, CTDR has the added benefit of preserving spinal motion, which can lead to better overall outcomes
Can CTDR be performed at multiple levels in the cervical spine?
Yes, CTDR can be performed at one or two levels in the cervical spine. Multi-level procedures are more complex and not suitable for all patients. A thorough evaluation is necessary to determine if you are a good candidate for multi-level CTDR
What are the long-term outcomes of CTDR?
Long-term studies show that CTDR provides sustained pain relief and functional improvement, maintaining motion at the treated segment. Patients typically experience a reduced need for additional surgery compared to those who undergo spinal fusion. This is due to the preservation of natural spinal motion, which helps to reduce stress on adjacent discs
Is CTDR suitable for elderly patients?
Age alone does not disqualify someone from CTDR. However, the overall health and bone quality of elderly patients must be considered. Conditions like osteoporosis might affect the stability of the implant. A comprehensive evaluation by a spine specialist will help determine if CTDR is appropriate
What is the success rate of CTDR?
The success rate of CTDR is high, with many studies reporting success rates of 80-90% in terms of pain relief and improved function. These rates are comparable to or better than those for spinal fusion, with the added benefit of motion preservation
Can CTDR be performed if I have osteoporosis?
Severe osteoporosis can affect bone integrity and stability of the implant, making CTDR less feasible. Each case needs to be evaluated individually, and other treatment options may be considered if osteoporosis is present
How does CTDR affect the range of motion in the neck?
CTDR aims to maintain the natural range of motion at the treated segment, unlike spinal fusion which restricts movement. This preservation of motion helps in maintaining overall spinal health and function
What are the signs of an artificial disc failing?
Signs of artificial disc failure include persistent or worsening pain, reduced range of motion, and symptoms of nerve compression such as numbness or weakness. Diagnostic imaging like X-rays or MRIs will be needed to confirm the failure
Can I drive after CTDR surgery?
You can typically resume driving once you are off pain medications and can comfortably and safely turn your head. This is usually within a few weeks post-surgery. However, it’s important to follow your surgeon’s specific advice on this matter
How does CTDR address nerve compression?
During CTDR, the damaged disc and any bone spurs that are pressing on the nerves are removed, which relieves pressure on the spinal cord and nerves. This alleviation of pressure helps reduce symptoms like pain, numbness, and weakness
Will I have a visible scar after CTDR?
The incision for CTDR is usually made in the front of the neck and is small, so any scar will typically be minimal and fade over time. Proper postoperative care and possibly scar treatment options can further reduce its visibility
What are the potential complications specific to CTDR?
Specific complications can include device dislocation, subsidence (sinking of the device into the vertebrae), and wear of the artificial disc. Although these complications are relatively rare, they can require additional surgical intervention if they occur
How soon after CTDR can I start exercising?
Light exercises and walking can usually be started within a few days after surgery. More vigorous activities should be introduced gradually and under the guidance of your physical therapist. This helps to ensure a safe and effective recovery
Can CTDR be performed on patients with previous spinal surgeries?
CTDR can be considered for patients with previous spinal surgeries, but each case needs to be evaluated individually. The previous surgery’s impact on the spine’s anatomy and stability will be crucial in determining feasibility and risks
How does CTDR affect overall spinal alignment?
CTDR aims to maintain or restore normal spinal alignment and curvature, potentially reducing the risk of further spinal issues
Are there non-surgical alternatives to CTDR for cervical disc disease?
Non-surgical treatments include physical therapy, medications, injections, and lifestyle modifications. Surgery is considered when these treatments fail to provide adequate relief
How do I choose the right surgeon for CTDR?
Look for a board-certified spine surgeon with extensive experience in performing CTDR. Check their credentials, patient reviews, and success rates with this specific procedure
What advancements are being made in CTDR technology?
Ongoing advancements include improved biomaterials, design enhancements for better motion preservation, and minimally invasive surgical techniques to reduce recovery time

Dr. Mo Athar
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